M-CSF/CSF1 Protein (AA 33-254)

N° du produit ABIN2115423

Cette protéine Recombinant M-CSF/CSF1 est produite dans Human Cells.

Aperçu rapide pour M-CSF/CSF1 Protein (AA 33-254) (ABIN2115423)

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Type de proteíne: Recombinant

Origine: Rat

Source: Human Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 33-254

Fonction: Recombinant Rat M-CSF/CSF1

Séquence: EVSEHCSHMI GNGHLQILQQ LIDSQMETAC LIEYKFVDQE QLDDPVCYLK KAFVLVQVII EETMRFKDNT PNANATERLQ ELSMKLNSCF IKDYKEQNEA CVQTYKESPL RLLEKIKNFF NETKNFLEKD WNIFSKNCND SFAKCSSRDV VTKPDCNCLY PKATPSSDLA SASPHQPPAP SMAPLADLAW DDSQRTEGSS LLPSDLPLRI EDPGSAKQRP PR

Attributs du produit: Recombinant Rat Macrophage colony-stimulating factor 1/MCSF/Csf1 produced by transfected human cells is a secreted protein with sequence (Gln33-Arg254) of Rat MCSF.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Autre désignation: MCSF

Sujet: Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
Synonyms: Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, CSF1

Poids moléculaire: 25.2 kDa

UniProt: Q8JZQ0

Pathways: Signalisation RTK